Fisetin 98% 20g

Fisetin (7,3′,4′-flavon-3-ol) is a plant flavonol from the flavonoid group of polyphenols. It can be found in many plants, where it serves as a yellow/ochre colouring agent. It is also found in many fruits and vegetables, such as strawberries, apples, persimmons, onions and cucumbers. Its chemical formula was first described by Austrian chemist Josef Herzig in 1891. 

How does Fisetin work?
Fisetin is a strong anti-oxidant that has also been proven to have potent senolytic effects. It has been shown to help remove senescent or damaged cells and to prevent the replication of damaged DNA. In doing so, it promotes human health and lifespan and has a role in aging and age-related diseases. Research has shown that Fisetin extends lifespan by reducing oxidative stress and increasing glutathione levels. It supports healthy aging and fights chronic disease. Research has shown that fisetin reduces senescence markers. It has twice the senolytic potency as quercetin. Fisetin, like other polyphenols such as resveratrol, is a sirtuin-activating compound and has been shown in laboratory studies to extend the life of yeast, worms, flies and mice. Fisetin has shown anti-cancer activity in studies on cells and model animals conducted in laboratories, and it appears to block the PI3K/AKT/mTOR pathway, along with other mechanisms to induce apoptosis activation, and prevent apoptosis resistance. Studies also have shown that fisetin induce cardiac regeneration by activating genes involved in cell proliferation and it potentially protects from ischemic damage after a heart attack and may help to prevent strokes. Finally fisetin (like quercetin) seems to prolong blood clotting time and thrombin time.

How to use Fisetin?
Purity over 98%. Natural product extracted from Rhus succedanea L. also known a Japanese Hazenoki tree, Sumac or wax tree. Recommended daily dosage up to 1,5g. Most trials have used daily dosages of 0,1 to 1,5g. Do not to exceed the stated recommended daily dose. Adverse reactions have not been recorded with these dosages. Fisetin is soluble in fat so it is recommended to take it with oil or fat to improve absorption. Store in a cool and dark place, away from children. Free measuring spoon included. We recommend using a spoon dedicated to fisetin, since it can color it. The spoon holds 0,3g of fisetin and is dishwasher safe. Food supplements should not be used as a substitute for a varied diet.